AB105. UPLC: an analytical technique to diagnose amino acid disorders accurately in biological samples
نویسندگان
چکیده
منابع مشابه
Using amino acid patterns to accurately predict translation initiation sites
The translation initiation site (TIS) prediction problem is about how to correctly identify TIS in mRNA, cDNA, or other types of genomic sequences. High prediction accuracy can be helpful in a better understanding of protein coding from nucleotide sequences. This is an important step in genomic analysis to determine protein coding from nucleotide sequences. In this paper, we present an in silic...
متن کاملUse of UPLC-ESI-MS/MS to quantitate free amino acid concentrations in micro-samples of mammalian milk
Although free amino acids (FAA) account for a small fraction of total nitrogen in mammalian milk, they are more abundant in human milk than in most formulas, and may serve as a readily available source of amino acids for protein synthesis, as well as fulfill specific physiologic roles. We used reversed phase Ultra Performance Liquid Chromatography (UPLC) coupled to electrospray ionization tande...
متن کاملConversion of trichloroacetic acid to dichloroacetic acid in biological samples.
Trichloroethylene (TCE) has been identified as an environmental contaminant in groundwater. Trichloroacetic acid (TCA), dichloroacetic acid (DCA), chloral hydrate (CH), trichloroethanol (TCOH), and trichloroethanol glucuronide (TCOG) have been identified as metabolites of TCE. Studies have shown that TCA and DCA are toxicologically significant metabolites that can induce liver tumors in B6C3F1 ...
متن کاملAmino Acid Disorders
Neurology (J. P. Mohrand and J. C. Gautier, Eds.), pp. 663– 667. Churchill Livingstone, New York. Nussenzweig, V., Sonntag, R., Biancalana, A., et al. (1953). Ação de corantes tri-fenil-metânicos sobre o Trypanosoma cruzi in vitro: Emprego da violeta de genciana na profilaxia da transmissão da moléstia de chagas por transfusão de sangue. O Hospital (Rio de Janeiro) 44, 731–744. Pagano, M. A., S...
متن کاملAmino acid disorders detected by quantitative amino acid HPLC analysis in Thailand: an eight-year experience.
BACKGROUND Amino acid disorders are a major group of inborn errors of metabolism (IEM) with variable clinical presentations. This study was aimed to provide the data of amino acid disorders detected in high-risk Thai patients referred to our metabolic lab from all over the country. METHODS From 2001 to 2009, we analyzed amino acids by HPLC in 1214 plasma and cerebrospinal fluid specimens. The...
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ژورنال
عنوان ژورنال: Annals of Translational Medicine
سال: 2017
ISSN: 2305-5839,2305-5847
DOI: 10.21037/atm.2017.s105